In an era marked by digital transformation and global disruptions, supply chain resilience has emerged as a critical capability for logistics service providers. This study investigates the role of strategic human resource management (HRM) and artificial intelligence (AI) in enhancing supply chain resilience, with supply chain agility as a mediating factor and organizational culture as a moderating variable. Drawing on data from 210 logistics service providers in Indonesia, the findings reveal that HRM strategies and AI adoption significantly improve supply chain agility, which in turn strengthens resilience. While agility mediates the relationship between HRM and resilience, and between AI and resilience, organizational culture does not significantly moderate the agility-resilience link. These results underscore the operational importance of agility and digital integration over cultural factors in emerging market contexts. The study contributes to the resource-based view and dynamic capability theory by highlighting how human and technological resources translate into resilience through agile processes. © 2025 IEEE.